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Flopping Trips / Set

If you flop trips with two same-suit cards on the board, you should be slightly o

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ver-betting the pot to put off those players on a flush draw. Its better to win the pot here than find

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ourself chip-committed against a flush on a more expensive turn or river. Again, if you flop trips but

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

with a straight draw on the board, you should bet / raise for the same reason. Some people choose to

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

low play their trips. This is not a good idea. Check-calling will not make you as much money as if you

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

et it out. Players with TPTK are likely to pay you off. Trips are dangerous because although they are l

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ikely to be the best hand on the flop, they might not be by the river. Bet them hard and aggressive but

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

be prepared to lay them down if the board makes four-to-a-flush.

Flopping a Straight

Don’t make it ch

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ap for the flush drawers out there to see the next card. If you flop a straight but there is danger of

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

being beaten by a flush, raise it up and play it aggressively while you have the best hand. If you flo

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

the low end of the straight, raise up the pot to try and protect against people drawing to the higher

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

nd of the straight. Examine the flop carefully. If it comes down non-connected and rainbow you can aff

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ord to play it a little slower. If it comes down same-suit and/or connected then play it hard to push o

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

t those drawing to a better hand.

Flopping a Flush

Bear in mind that it takes 5 cards to make a flush

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

there are only 8 cards left of that suit in the deck. It is possible but unlikely that another opponen

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

t also has a flush. Play low card flushes with caution and get your money in the pot while you still ha

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

e the best hand. If the flop makes three to a flush you should bet / raise to gain information and to

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

in the pot early on. If your flush is low (7 or lower) then be prepared to lay it down should the boar

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

d make four-to-a-flush and someone is betting it hard. You are most likely up against a better flush.

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

lthough extremely unlikely, keep your eyes out for potential straight flushes. They do sometimes happen

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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