I Suggest - Automotive

Do you ever get the feeling that you as a consumer are being tested to see just how much you will pay when it comes to the skyrocketing gasoline

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

prices we are continually facing? It seems that everyday the media is reporting that the cost of a barrel of crude oil is climbing higher and

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

igher! This, of course, causes an immediate inflationary effect on the price of what refineries and fuel distributors charge you and I for the f

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

inished fuel product that we must purchase in order to merely go about our daily routine. For most of us, this has become an all too familiar s

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ene as we are reluctantly forced to view our car's fuel gauge and acknowledge that the little "E" stands for "Empty", not "Extra". Then the rea

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

horror begins as we drive past station after station, looking for that 'bargain', only to realize that with each passing gas station, gasoline

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

prices are rising higher and higher, and since we are now running on fumes, we can't risk going back!

While it is understandable that a rise in

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

the cost of crude oil, (the main ingredient necessary to manufacture fuel products, such as gasoline and diesel), will result in higher future f

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

uel prices, what I do not find understandable is the practice of charging more for the gasoline and diesel fuel that has already been produced f

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

om crude oil purchased before the rise occurred.

Gasoline producers and distributors need to pick a line of defense and stick to it: If they a

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

e going to argue the need to raise prices on the processing of the crude oil they just paid more for, so be it. But then they should be willing

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

to sell for less their current supplies of fuel that were produced from crude oil purchased before their costs went up. Instead they argue tha

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

they must charge the higher price now because it will cost them more to replace their current supplies. If that is the case, why are they not

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

willing to sell their current holdings for less on those rare occasions when the cost of crude oil drops, knowing that they will be able to repl

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ce it for less? Their answer? Because they had to pay more to produce the fuel they have on hand, they must recoup their costs as they sell it

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

They can call it what they like; I call it price gouging!

Just when you think they can't possibly raise fuel prices any higher, you're proven

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

wrong, and there is nothing you can do about it. Or is there? More and more consumers are actually starting to home-brew their own fuels, suc

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

as "bio-diesel". Others are finding that certain inexpensive fuel additives can effectively increase their vehicles' mileage by helping the fu

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

el burn more completely, which increases horsepower and lowers emissions, thus raising the efficiency of whatever fuel their engine consumes.

A

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

though we as consumers cannot directly take control of runaway gasoline prices, we can take reasonable steps to make sure our fuel-dollars count

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Don't violate one of the main rules in estate planning: whenever there is a major change in your life situation (a life changing event such as the death of a close family member) you should (probably must) review your estate plan to see what changes are required.

Eleven clues you can look for to determine if a home business opportunity is legitimate or a scam.

Did you get all the book sales you wanted last year? Think about the time, effort and money you invested. Which one's paid off? Which were losers? Look over last year and write your marketing duds and successes down!

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