I Suggest - Pets

My cat Spike is very laid back . He’s a lover, not a fighter, so it was with surprise that one morning as I was feeding him his daily ration of cat food, I saw two scratches on his nose. He ate the food like h

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

e was famished, instead of taking a few bites then going somewhere to think the situation over. Normally he would then come back to his bowl and begin to eat again. At the time I didn't know there were racco

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ns eating his food at night.

Spike sleeps in the garage. He has a cat door to the outside, so he comes and goes as he pleases. Only on the coldest winter nights does he sleep in the house, preferring the sol

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

itude of his own kingdom where there is always silence after dark. His quiet time was shattered one night a couple of hours after dinner. I heard a noise in the garage that sounded like something falling fro

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

a shelf. I opened the door to the garage and saw a large raccon scurrying from the cat’s bowl to the opening in the pet door. He scooted through the door to the outside, then turned around and stuck his hea

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

d back through the door, staring at me as if I should be sorry for interrupting his dinner.

The next day surveying the damage to my exterior door, where the raccon had scratched and torn at the pet door to get

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

inside the garage, I did some studying about the subject of raccoon removal. I found out that they are nocturnal animals, sleeping all day and feeding and roaming at night. I also learned that there are ways

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

to remove raccoons without shooting them. They are as follows:

Remove their food supply! This sounded like such a good idea that I tried it. I brought the cat’s dish into the house. That didn’t deter the

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

accoon in the least. He couldn't see the food, so he chewed the lid off the five gallon containers that held the cat food, scattering it all over the garage. This dampened my spirits somewhat, but I was deter

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

mined to drive him from our house forever!

Play the radio loudly in the areas the raccoon has invaded! They will think someone is talking and stay away! I tuned the radio in the garage to a station that play

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

d rap music all night, then turned up the volume. I figured if that didn’t do the trick nothing would. It didn’t work! Somehow he climbed up a bookshelf onto the top of a refrigerator where I had stored the c

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

t food. He pushed it off onto the floor, dry cat food bouncing on the concrete floor like raindrops on a roof.

Trap the animals. I called the city animal control people and they brought me a trap. This was

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

a big cage that would catch the raccoon without hurting it. The theory is that the raccoons would enter the trap, stepping on the trip mechanism as they ate the bait, (cat food), thus tripping the trap door.

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

he raccoons would be caught, the city would then remove the animal to a safe place, miles away from my house and all would be peaceful again. Wrong! The only thing I caught was my cat Spike! Twice!

I learned

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

that those traps do work, but raccoons are very intelligent. You have to put concrete blocks or some kind of barrier around the sides of the trap so they won’t put their paws into the cage and grab the food w

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

thout springing the trap. Raccoons have paws with fingers that enable them to grasp food and stuff it into their mouths.

By this time I realized I had a family of raccooons. By now I had seen five; two adult

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

s and three young ones. The young ones let me take their pictures while munching on Spike's cat food. I reward them for allowing me a photo shoot. The older ones wait patiently outside the door until I finish

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

shooting. They’ll finish up the food when I go back into the house. Spike the cat is sprawled in an old chair, yawning at the raccoons.

My wife thinks I’m nuts to have fallen under the spell of the adolescen

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

t raccoons. Since one of the young raccoons tries to get into the house every time the Maybe I am, but they are a lot of fun. I’ve ordered a sure-fire raccoon repellant that I know will work. It’s coyote ur

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ne. Sprinkled around the area the raccoons frequent, it will scare them away. They’re afraid of coyotes because they are one of the natural predators of raccoons. If this doesn't work, I'll order wolf urine

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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I Suggest - My Cat's Late Night Visitors!

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