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Betta fish or Betta Splendens or Siamese fighting fish are native to the lands of Thailand, Vietnam, China, and other related regions. The

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

y were first spotted in Cambodia, Thailand. In fact, Cambodia use to be known as Siam, hence the name Siamese fighting fish. They are call

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

d fighting fish, because they are extremely territorial. Males cannot be kept together because all they will do is fight until one or both

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

re seriously injured. Betta fish can grow to three inches are famous for their long flowing fins.

You can pick out a betta fish right awa

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

in a tank because they look like something completely different from other fish. A betta fish is usually in shades of blues, reds, purples

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

or sometimes-even white. The way to spot a male is because males are more vibrant in color and their fins are longer. Females also have so

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

e vertical stripes when healthy. If you think that you may be looking at a female betta fish in the pet store, but don’t see the stripes, y

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ou may want to think again about purchasing one since it’s probably sickly. Betta fish prefer to eat live foods, but flakes or frozen foo

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

s will be just as fine.

Why are betta fish so popular as pets? Well the first thing that will attract an aquarium lover to betta fish is

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

he way they look. They have rich colors and dramatic fins. Their size isn’t bad either since they are considerably small. Bettas also have

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

distinct personaility. They wag their tails like a pup and act just as cute. Remember, they have a mind of their own as well. To see a bet

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

a’s true personality it has to be happy.

When betta fish are happy and healthy you will notice that they are playful and they move with su

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

h grace. Unhappy and unhealthy betta fish will move extremely slow and in a very depressing way. Since there are many betta fish that are b

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

eeded specially to get certain colors that aren’t the traditional colors, you will find that you will soon be collecting these beauties. T

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

he only thing is that you have to give them enough tank space and also surface space. Surface space is important because betta fish cannot

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

reath while in the water, but they breath directly from the surface.

When it comes to betta fish, you will need to know that there are onl

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

a few things to keep in mind. First, you need to keep in mind the temperature. You need to keep the tank between 75f-85F. The ammonia l

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

vels are sometime to worry about. Often new tanks will make the tank build up high levels of ammonia, which will kill, or make the fish sic

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

. This is easily taken care of if you just make sure that the tank is washed properly and the water is changed on a regular basis. If the w

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ter is good, then your betta fish will surely live their full lifespan of two or three years. They could even live-longer with proper care

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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