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Following the legendary tradition of large armies being trounced by small forces - think of 1 angel destroying 185,000 Assyrians, or Samson slaying 1000 Philistines with the jawbone of an ass - we can overcome the 30 Ways That Parents Can Exasperate Their Children with just 3 powerful qualities: Empathy, Respect
According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
g>, and Patience. By their very nature, these three qualities overlap, but by so doing, they intertwine and bind together to form themselves into a formidable entity.

EMPATHY Empathy is a difficult skill to master, but once we take a hold of it, it becomes our most powerful tool, with spectacular results. The best def
; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in
nition is this: Empathy is the ability to comprehend with accuracy the precise thoughts and motivations of other people - our children - in such a way that they would say, "Yes, that is exactly where I'm coming from." When we have this extraordinary knowledge, it helps us to accept without anger why our children act the way they do even though
lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

heir actions may not be to our liking. Empathy is us, as parents, attempting to see the world through our child's eyes.

Empathy does not ask us to feel what a child feels. It does not necessarily demand that we have experienced what our child has experienced - in fact such an attitude can often serve as a hindrance. Life as a teenager fifteen or twenty
here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
years ago is not what it is now. "I know how you feel," is not helpful - nobody knows how another person feels because we are all different. Empathy simply asks us to understand and appreciate what our child is going through. Accept their feelings as real and, in so doing, we help them to cope. We can do this by listening with understa
d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro
ding, and giving a name to their feelings when the occasion warrants it.

Though we might have to limit some unacceptable actions, we can certainly accept all of a child's feelings. Helping them recognize their real feelings, even negative ones, is a real benefit to them. Feelings are not right or wrong. Feelings just
ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
are. How we deal with them is what counts. Empathy helps us understand ambivalence - that more than one feeling can be experienced at the same time, or that a young mind can change in an instant. We understand that feelings are unique to each child. Showing empathy builds up our child's confidence, enabling them to trust their own feelings and their ow
easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
n abilities. It doesn't necessarily mean agreeing with them, but it tells them their feelings are important. Their feelings matter, they don't shock or frighten us. This will produce children who feel heard and understood.

There is great strength and deep security in realizing, "My parents understand."

RESPECT Respect is a w
nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
nderful thing. When defined it takes on a compelling shape. Respect is "the condition of being honoured or esteemed; an attitude of admiration; A courteous expression of esteem". Esteem is "a feeling of delighted approval and liking." So, respect is found in our attitude and our expressions. It tells our children that we don't just love them, we lik
and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
them. It lets them know that they have our approval. We can see that giving our children such respect is going to fill them with confidence and personal strength.

Children are people. They are individuals. It may seem like an obvious statement to make, but, as parents, we occasionally need to be reminded. It means we know that our young ones are
ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
triking out on their own and seeking independence, and we are there to help them do that. We do not want to stifle it or hold it back.

When we respect our children as individuals in their own right we are more likely to avoid words that evaluate, or judge. We describe what we see and feel, from praise to anger to crit
ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a
icism. We focus on actions and solutions, not personality. Rather than pointing out what is wrong with a child - calling him a liar to make him honest, lazy to make him industrious - we treat a child as if he already is what he is capable of becoming.

Respect allows our children to work out solutions for themselves. As Dr Ginott woul
dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod
say: Don't just do something. Stand there. It does not need to shield them from unhappiness and disappointment, but gives them space to face these tribulations, and persevere. Then they are able to say to themselves, "Mum and Dad believe in me. They trust that I can endure, that I can cope."

Respect listens to a child's point of view without
cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
idiculing or belittling. It allows a child privacy, a place for their own private thoughts. It gives children room for change and growth, rather than pigeon-holing with a role or a label.

PATIENCE It takes patience to stand back and allow a child time to accomplish a seemingly simple task - tying a lace, putting a shoe on the right fo
tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
ot, unzipping a coat. It takes patience to allow a child to make the same mistake time and time again. It takes patience to believe that a child is not just being willfully disobedient, but is quite simply at a time in their life when they are eager to have more independence and yet they are struggling with the notion of what to do with it.

Patience un
t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
erstands a small child's ambivalence as he seeks for independence and yet shys away from it, fears it. It understands his mood swings as he tries to navigate the difficult waters of growing up. Patience does not mean that we never get angry - that would be unreasonable - but it does mean that even in our anger we remain respectful.

Patience will allow
ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust
us to talk less and listen more. It will counteract our fear of letting go, of giving children room to make mistakes, fight and disagree.

Patience appreciates that curiosity develops quicker than memory. It believes that a child will learn...eventually, whilst accepting that it may take repeating something hundreds of times.

Children model t
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
hemselves on their parents, they do most of their social learning from their parents. They will take in every detail of what we are like as a person - not just of what we are like with them, but with other people as well. They will not do as we say, they will do as we do. It is not only our tone of voice or reassurance of love that is important - it is
.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
he words we use and the actions we take. We want to demonstrate the kind of respectful communication we hope our children will use with themselves and with other people - now, as teenagers and as adults. If we conduct ourselves with Empathy, Respect, and Patience, then these are the qualities that our
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip
hild will develop. And we will go a long way to defeating many of the 30 Ways That Parents Can Exasperate Their Children.

Parents are in the honourable position of helping their child grow into a respectful and patient adult who is aware of other people's feelings. This is indeed a noble pursuit

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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I Suggest - How Parents Can Avoid Exasperating Their Children

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